THE FIRST ASYMMETRIC-SYNTHESIS OF ZYLOXYCARBONYL-METHYLAMINO)-2'-PHENYLETHYL]OXIRANE - A PROMISING BUILDING-BLOCK FOR THE SYNTHESIS OF PEPTIDE MIMICS

Citation
C. Beier et al., THE FIRST ASYMMETRIC-SYNTHESIS OF ZYLOXYCARBONYL-METHYLAMINO)-2'-PHENYLETHYL]OXIRANE - A PROMISING BUILDING-BLOCK FOR THE SYNTHESIS OF PEPTIDE MIMICS, Synlett, (1), 1998, pp. 41
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
09365214
Issue
1
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):1<41:TFAOZ>2.0.ZU;2-V
Abstract
The threo N-methyl oxirane 5 was prepared from (S)-N-methyl phenylalan ine by bromoketone reduction or by epoxidation routes. The unexpected stereochemical result of the reduction of bromoketone 7 leading to the threo isomer is discussed.