DR(A) (CROMER-RELATED BLOOD-GROUP ANTIGEN)-INCOMPATIBLE RENAL-TRANSPLANTATION

Background and objectives: Cromer system antigens, a series of blood g roup antigens of very high frequency, are not considered to be clinica lly significant in transfusion. La renal transplantation only the ABO blood group antigens are considered essential, The Drori blood group a ntigen is present in serum and has been found to reside on the renal t ubular basement membrane and Bowman's capsule, The effect of anti-Dr(a ) on the renal parenchyma has not been evaluated, Materials and method s: A unique case of renal transplantation of an incompatible Dr(a+) ki dney to a Dr(a-) patient with anti-Dr(a) in her serum is presented, Re sults: Graft function was immediately good, The titer of anti-Dr(a) re mained unchanged following transplantation. Conclusion: The successful outcome of a case afa Drori (Dr(a))-incompatible kidney transplantati on confirmed the tack of clinical significance-of the anti-Dr(a) relat ing to transplantation.