CONTROL OF ACTIN DYNAMICS

Authors
Citation
Mf. Carlier, CONTROL OF ACTIN DYNAMICS, Current opinion in cell biology, 10(1), 1998, pp. 45-51
Citations number
55
Categorie Soggetti
Cell Biology
ISSN journal
09550674
Volume
10
Issue
1
Year of publication
1998
Pages
45 - 51
Database
ISI
SICI code
0955-0674(1998)10:1<45:>2.0.ZU;2-3
Abstract
Actin-based motility processes are tightly-linked to the rapid turnove r of actin filaments. Factors that control the steady state of actin a ssembly, such as capping proteins and actin-depolymerizing factor/cofi lin, directly affect motility. Actin-depolymerizing factor increases t he treadmilling of actin filaments in vitro and in vivo. Cellular fact ors that are involved in linking initiation of barbed end assembly to cell signaling are being identified using Listeria monocytogenes and S accharomyces cerevisiae as model systems.