INTERMEDIATE FILAMENTS AND THEIR ASSOCIATED PROTEINS - MULTIPLE DYNAMIC PERSONALITIES

Authors
HOUSEWEART MK CLEVELAND DW
Citation
Mk. Houseweart et Dw. Cleveland, INTERMEDIATE FILAMENTS AND THEIR ASSOCIATED PROTEINS - MULTIPLE DYNAMIC PERSONALITIES, Current opinion in cell biology, 10(1), 1998, pp. 93-101
Citations number
60
Categorie Soggetti
Cell Biology
Journal title
Current opinion in cell biology → ACNP
ISSN journal
09550674
Volume
10
Issue
1
Year of publication
1998
Pages
93 - 101
Database
ISI
SICI code
0955-0674(1998)10:1<93:IFATAP>2.0.ZU;2-4
Abstract
A fusion of mouse and human genetics has now proven that intermediate filaments form a flexible scaffold essential for structuring cytoplasm in a variety of cell contexts. In some cases, the formation of this s caffold is achieved through a newly identified family of intermediate- filament-associated proteins that form cross-bridges between intermedi ate filaments and other cytoskeletal elements, including actin and mic rotubules.