Children of HIV-infected women are likely to be profoundly affected by
their mothers' infection, regardless of their own infection status an
d their number will increase with the spread of infection among women
in Europe. This article describes the family circumstances and social
care of 1,123 children born to HIV-infected women enrolled in the Euro
pean Collaborative Study and followed prospectively from birth. Most m
others were white, married or cohabiting, asymptomatic and had a histo
ry of drug use, with 45% currently using injecting drugs at the time o
f enrolment. Seventy percent of children were cared for by their mothe
rs and/or fathers consistently in their first four years of life, but
by age eight an estimated 60% will have lived away from their parents
(i.e. with foster or adoptive parents, other relatives or in an instit
ution). Whether or not a child was infected did not influence the like
lihood of living in alternative care. Maternal injecting drug use, sin
gle parenthood and health status were the major reasons necessitating
alternative care. The type of alternative care varied according to mat
ernal characteristics, child's age and geographic location. The mother
s of 98 children had died and average age at maternal death was four y
ears.