Science career choice is partly determined by precursors such as enrol
lment in science and mathematics courses, which are, in turn, determin
ed by factors such as attitudes toward science, participation in scien
ce activities, and science career preference. Participants were 1,501
students, Grades 4 through 10, from a large, national intervention stu
dy. Independent variables were gender and grade. Dependent variables m
easured attitude, activities, and career preference. Multivariate, uni
variate, and discriminant analysis and chi-square tests of association
were used. Girls were less likely than boys to see science as a male
activity or to believe they had not received serious attention from th
eir science teachers. In contrast, girls were less likely than boys to
see science as a fun puzzle to be solved. On three out of four measur
es of interest in Realistic and Investigative careers (Holland, 1997),
girls showed less interest than boys. There were no gender difference
s for science activities and no gender-by-grade interaction effects. R
esults confirm the complex nature of attraction to a career in science
and shed some light on differences between boys and girls in the unde
rstructure of science career interest.