Aim. To assess the potential for preventing major causes of premature
death, disease and injury in New Zealand. Methods, Population attribut
able risks for major modifiable risk factors for important causes of d
eath and disease in New Zealand were calculated using available nation
al and international data on the relative risk of disease and the prev
alence of risk factors in the relevant New Zealand population. Attaina
ble changes in risk factor prevalences were used to model population a
ttributable risks over the next five years. These estimates were then
used to estimate potential reductions in absolute numbers of deaths fr
om major diseases. Results, High population attributable risks were fo
und for several disease/risk factor combinations: smoking and lung can
cer (81% in Maori), smoking and coronary heart disease (44% in Maori),
smoking and sudden infant death syndrome (49% in Maori); raised serum
cholesterol and coronary heart disease (58%); physical inactivity and
coronary heart disease (35%), physical inactivity and diabetes (30%),
physical inactivity and colorectal cancer (33%), physical inactivity
and fractured neck of femur (65%); obesity and hypertension (66%), obe
sity and diabetes (46%); lack of fruits and vegetables and stomach can
cer (46%), and colorectal cancer (34%). The estimated, readily attaina
ble reduction in absolute numbers of annual deaths due to decrease in
risk factor prevalence was greatest for smoking (457 deaths), followed
by hypertension (326), physical inactivity (303) and raised serum cho
lesterol (142). Conclusion. There is significant scope for reducing mo
rtality from major non-communicable diseases although for some disease
s such as the cancers, there will be a time lag of many years before t
he full benefits are realised. Together, reducing the prevalence of sm
oking, hypertension, physical inactivity and raised serum cholesterol
would result in 1228 fewer deaths per year.