Derivatives of 1-fluoroaziridine-2,2-dicarboxylic acid 10-14 have been
synthesized for the first lime and characterized by spectroscopic met
hods; nucleophilic reactions of dimethyl 1-fluoroaziridine-2,2-dicarbo
xylate, such as transesterification and amidation, occur predominantly
at the carboxy group trans-oriented with respect to the N-substituent
.