HIGHLY EFFICIENT SYNTHESIS OF PHOSPHORODITHIOATES DERIVED FROM 3'-THIOTHYMIDINE BY ANHYDRO-RING OPENING OF 2,3'-ANHYDRO-5'-O-TRITYLTHYMIDINE WITH O,O-DISUBSTITUTED PHOSPHORODITHIOIC ACIDS

Authors
DABKOWSKI W MICHALSKA M TWOROWSKA I
Citation
W. Dabkowski et al., HIGHLY EFFICIENT SYNTHESIS OF PHOSPHORODITHIOATES DERIVED FROM 3'-THIOTHYMIDINE BY ANHYDRO-RING OPENING OF 2,3'-ANHYDRO-5'-O-TRITYLTHYMIDINE WITH O,O-DISUBSTITUTED PHOSPHORODITHIOIC ACIDS, Chemical communications, (3), 1998, pp. 427-428
Citations number
29
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
3
Year of publication
1998
Pages
427 - 428
Database
ISI
SICI code
1359-7345(1998):3<427:HESOPD>2.0.ZU;2-B
Abstract
Thymidine 3'-S-phosphorodithioate 4 and dithymidine-3'-S-phosphorodith ioate 7 derived from 3'-thiothymidine are synthesized in excellent yie ld under mild conditions by the nucleophilic ring opening of 2,3'-anhy drothymidine with phosphorodithioic acids.