COMPARATIVE TEXTUROMETRIC ANALYSIS OF HYDROGELS BASED ON CELLULOSE DERIVATIVES, CARRAGHENATES, AND ALGINATES - EVALUATION OF ADHESIVENESS
Citation
B. Vennat et al., COMPARATIVE TEXTUROMETRIC ANALYSIS OF HYDROGELS BASED ON CELLULOSE DERIVATIVES, CARRAGHENATES, AND ALGINATES - EVALUATION OF ADHESIVENESS, Drug development and industrial pharmacy, 24(1), 1998, pp. 27-35
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
SICI code
0363-9045(1998)24:1<27:CTAOHB>2.0.ZU;2-#
Abstract
This paper reports a texturometric study of hydrogels based on cellulo
se derivatives, carraghenates (with or without Na+ or K+), and alginat
es (associated or not with Ca++). The stiffness, elasticity, and cohes
iveness are evaluated and the influence of the nature and the concentr
ation of gelling agent on the adhesiveness, an indicator of bioadhesio
n, is discussed. The highest adhesiveness values are found among the s
emi-stiff gels, particularly with those based on either sodium or pota
ssium alginate, or cellulose derivatives. The least satisfactory resul
ts are obtained with the formulations associating carraghenates and Na
+ or K+.