Background/Aims: Major abdominal surgery in elderly patients has tradi
tionally been thought to carry a high operative risk. Recent data, how
ever have suggested that with proper selection, elderly patients can w
ithstand pancreatic resection. Methodology: The medical records of 102
patients who underwent pancreatic resection for pancreatic or periamp
ullary tumors were retrospectively reviewed. Twenty-nine patients were
aged 70 years or older (mean age: 74 years) and 73 patients were youn
ger (mean age: 56 years). Concomitant comorbid conditions were evaluat
ed in the patients of both groups, and no significant differences were
identified. A pancreaticoduodenectomy was performed in 81 cases and a
total pancreatectomy in. 21. Results: The operative mortality rate wa
s 0% in the older patients and 6.8% in the younger patients. Major com
plications occurred in. 28% of-the patients. There were no significant
differences in morbidity among the true age groups. The overall actua
rial survival curves showed similar trends in both groups. Conclusions
: With appropriate preoperative selection, pancreatic resection can be
performed with low operative risk in elderly patients. Chronological
age alone should not be considered an absolute contraindication for pa
ncreatic resection.