EFFECT OF NITRIC-OXIDE ON POLIOVIRUS INFECTION OF 2 HUMAN CELL-LINES

Authors
LOPEZGUERRERO JA CARRASCO L
Citation
Ja. Lopezguerrero et L. Carrasco, EFFECT OF NITRIC-OXIDE ON POLIOVIRUS INFECTION OF 2 HUMAN CELL-LINES, Journal of virology, 72(3), 1998, pp. 2538-2540
Citations number
24
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
72
Issue
3
Year of publication
1998
Pages
2538 - 2540
Database
ISI
SICI code
0022-538X(1998)72:3<2538:EONOPI>2.0.ZU;2-L
Abstract
The role of nitric oxide after poliovirus infection of the human HeLa (carcinoma) and U937 (promonocytic) cell lines has been analyzed, Both types of cells produced detectable levels of nitric oxide after polio virus infection. However, this production was not sufficient to limit viral productivity. On the other hand, pretreatment with the nitric ox ide donor glycerine trinitrate lengthened the course of poliovirus inf ection.