Heterosexual transmission of a murine leukemia virus mixture named LP-
BM5 MuLV, which is known as the murine AIDS virus,,vas investigated. O
ur results indicated that the heterosexual transmission of LP-BM5 MuLV
occurs in both directions with high frequency and that the frequencie
s of virus transmission in the cervix and penis are higher than those
in other genital organs. The results suggested that infection by LP-BM
5 MuLV via heterosexual transmission may initially take place at parti
cular retrovirus-sensitive sites (cells) in the genital organs.