Plant genetic engineering offers opportunities for the creation of ins
ect-resistant plants by insertion and expression in planta of entomopa
thogenic proteins. Two main approaches to obtain such plants have been
explored. The first one involves the use of delta-endotoxin coding se
quences originating from the bacterium Bacillus thuringiensis. The sec
ond approach uses plant-derived genes, such as those encoding enzyme i
nhibitors or lectins. Much work throughout the world is devoted to obt
aining plants of different species expressing such genes and showing r
esistance to insect pests. Research projects under development, and an
assessment of the situation and of the problems encountered on the wa
y to a commercial use of such transgenic plants are discussed in this
review. (C) 1998 Elsevier Science Ireland Ltd.