K. Kobayashi et al., EFFECTS OF L-THEANINE ON THE RELEASE OF A LPHA-BRAIN WAVES IN HUMAN VOLUNTEERS, Nippon Nogei Kagakukaishi, 72(2), 1998, pp. 153-157
L-Theanine is an amino acid found in green tea leaf and in its infusio
n, and is known to control excitement caused by caffeine. It is also k
nown that the oral administration of L-theanine to rats results in a d
ecrease of serotonin and increase of catecholamines in their brain. L-
Theanine has been confirmed to be safe in animal experiments. We found
recently that oral intake of L-theanine caused a feeling of relaxatio
n among the human volunteers examined. These observations led us to do
experiments on the effects of administration of L-theanine on the bra
in electric waves. Eight female university students were selected as v
olunteers. Four of them were ranked to be Grade I(the highest anxiety)
and the remaining four, Grade V (the lowest anxiety) in an investigat
ion done by the manifest anxiety scale method. A dose of oral administ
ration of 200 mg of L-theanine dissolved in 100 ml of water resulted i
n the generation of a-electric waves in the occipital and parietal reg
ions of the brains of the subjects. The emission intensity of a-brain
waves (integrated as a function of investigation times and area) was s
ignificantly greater in the group of Grade I than that of Grade V. The
se results indicate the possibility for L-theanine to be applied to fo
ods and beverages as a new type of functional food ingredient for its
relaxation effect.