ASYMMETRY OF CORTICAL EXCITABILITY REVEALED BY TRANSCRANIAL STIMULATION IN A PATIENT WITH FOCAL MOTOR EPILEPSY AND CORTICAL MYOCLONUS

Authors
INGHILLERI M MATTIA D BERARDELLI A MANFREDI M
Citation
M. Inghilleri et al., ASYMMETRY OF CORTICAL EXCITABILITY REVEALED BY TRANSCRANIAL STIMULATION IN A PATIENT WITH FOCAL MOTOR EPILEPSY AND CORTICAL MYOCLONUS, ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 109(1), 1998, pp. 70-72
Citations number
8
Categorie Soggetti
Neurosciences,"Engineering, Biomedical
Journal title
ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY → ACNP
ISSN journal
0924980X
Volume
109
Issue
1
Year of publication
1998
Pages
70 - 72
Database
ISI
SICI code
0924-980X(1998)109:1<70:AOCERB>2.0.ZU;2-B
Abstract
Motor cortex excitability was analyzed with transcranial stimulation i n a patient with motor focal epilepsy and cortical myoclonus originati ng from the right motor cortex. The motor threshold to single transcra nial magnetic shocks, but not to electric stimuli, was higher in the e pileptic motor cortex than the normal left motor cortex. Single magnet ic shocks elicited a short cortical silent period (50 ms) in the epile ptic motor cortex. Paired magnetic stimuli also showed reduced cortico -cortical inhibition. These findings reveal an asymmetry in cortical e xcitability presumably due to impaired inhibition in the epileptic mot or cortex. (C) 1998 Elsevier Science Ireland Ltd.