Purpose: Early amputation has been suggested to be the optimal treatme
nt for severe combined vascular and neural injuries of the proximal up
per extremity. This retrospec tive study was done to evaluate the long
-term clinical outcome of our policy of limb salvage by revascularizat
ion and delayed treatment of neural injuries. Methods: forty-six patie
nts with neural and vascular trauma to the upper extremity were treate
d at our institution. All of these patients had aggressive treatment d
irected at limb salvage with restoration of vascular supply and nerve
function. Long-term vascular and neurologic outcomes were recorded. Ne
urologic deficits were validated by the American Medical Association's
standardized disability impairment scale (0% to 100%). Results: The r
ate of preoperative disability was 83%, which improved to 52% (p < 0.0
1) after treatment (mean follow-up, 43 months). Overall, 87% showed im
provement. Conclusion: These results suggest that early amputation sho
uld not be performed unless there is massive tissue loss or an attempt
at limb salvage might endanger Life. final outcomes cannot be predict
ed on the basis of initial clinical presentation. As a group, the majo
rity of these patients improved with aggressive intervention. (J Vasc
Surg 1998;27:43-9.).