A multicenter study of 71 patients with aneurysmal bone cyst (ABC) sho
wed that 85% of cases were characterized by typical radiological featu
res consisting of a sharply marginated, expansile, eccentric lesion wi
th a honeycomb structure that displaced the soft tissues without disru
pting the cortex. Sites of involvement were the long tubular bones of
the limbs (72%; femur, 30%; tibia, 18%, humerus, 11%), short bones (24
%), and flat bones (4%). The bone segments involved were the metaphysi
s and diaphysis in 43% of cases, the epiphysis and metaphysis in 20%,
the metaphysis in 18%, the diaphysis in 11%, and the epiphysis, metaph
ysis, and diaphysis in 8%. Age was younger in patients with involvemen
t of the metaphysis or metaphysis and diaphysis (12-13 years) than in
those with involvement of the epiphysis, metaphysis, and diaphysis (20
-28 years). Some patients, especially those with secondary ABCs, had a
typical features on plain radiographs suggestive of a malignant tumor.
Computed tomography was helpful in demonstrating a low attenuation co
efficient within the tumor that increased slightly after intravenous a
dministration of a contrast agent. A fluid-fluid level was seen in one
of the four patients who had computed tomography; this finding is hig
hly suggestive of ABC, the only other lesion in which it has been repo
rted being telangiectatic osteosarcoma. One patient was successfully t
reated by arteriography with embolization, which induced minimal bleed
ing. Magnetic resonance imaging was not used in this series.