THEORETICAL APPROACHES AND PRACTICAL INVESTIGATIONS IN CARBOPOL BUCCAL PATCHES FOR DRUG-DELIVERY

Authors
GUO JH COOKLOCK KM
Citation
Jh. Guo et Km. Cooklock, THEORETICAL APPROACHES AND PRACTICAL INVESTIGATIONS IN CARBOPOL BUCCAL PATCHES FOR DRUG-DELIVERY, Drug development and industrial pharmacy, 24(2), 1998, pp. 175-178
Citations number
13
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
Drug development and industrial pharmacy → ACNP
ISSN journal
03639045
Volume
24
Issue
2
Year of publication
1998
Pages
175 - 178
Database
ISI
SICI code
0363-9045(1998)24:2<175:TAAPII>2.0.ZU;2-E
Abstract
This paper describes the theoretical approaches in the peeling test me thod which can be used to evaluate the bioadhesive patches for buccal drug delivery purposes. The effects of patch thickness and the peeling rate on the bioadhesion of buccal patches were investigated from a th eoretical point of view. The influence of a crosslinking agent on the swelling and bioadhesive properties of the patches was also evaluated.