K. Wassermann et al., EMERGENCY STENTING OF MALIGNANT OBSTRUCTION OF THE UPPER AIRWAYS - LONG-TERM FOLLOW-UP WITH 2 TYPES OF SILICONE PROSTHESES, The Annals of otology, rhinology & laryngology, 107(2), 1998, pp. 149-154
We report on 10 patients with severe malignant ''mixed-type'' obstruct
ion of the proximal trachea or distal trachea plus both main stem bron
chi. They had far-advanced inoperable tumors (esophageal cancer in 4 p
atients, lung cancer in 3, and recurrent laryngeal, uvular, and thyroi
d cancers in 1 each). Emergency treatment consisted of a dilating boug
ie maneuver followed by the insertion of a large one-way (4 patients)
or Y-shaped (6) silicone prosthesis. Subsequent to the intervention, t
here was long-lasting clinical improvement. The median survival from s
tent insertion was 8 months for all patients irrespective of tumor typ
e; it was 5 months for lung carcinoma patients and 8 months for those
with esophageal cancer. The results are in accordance with those of ot
her studies using different therapeutic modalities. Stent exchange pro
ved necessary in 5 patients. The main reasons were continuing tumor gr
owth beyond the proximal and distal boundaries and recurrent productiv
e bronchial infection. Patients died of pneumonia (4 patients), pulmon
ary lymphangitic spread (1), heart failure (2, one of whom also had pn
eumonia), and fatal hemorrhage (1). As of December 1995, 3 patients we
re still alive, 2, 5, and 8 months after stent implantation. As eviden
ced by clinical efficacy and length of palliation, endoscopic placemen
t of silicone-based one-way and bifurcated prostheses in far-advanced
tumor of the central airways is technically feasible and ethically jus
tifiable.