Bj. Rounsaville et al., PERSONALITY-DISORDERS IN SUBSTANCE-ABUSERS - RELATION TO SUBSTANCE USE, The Journal of nervous and mental disease, 186(2), 1998, pp. 87-95
Previous studies have documented high but variable rates of DSM person
ality disorders (axis TT) in clinical samples of substance abusers. Di
stinguishing between personality disorder symptoms that are independen
t versus substance-related CSR) is a particular challenge for diagnosi
ng comorbid axis II disorders in substance abusers. DSM-IV guidelines
currently recommend excluding axis II symptoms that are accounted for
by an axis I disorder, including a substance use disorder. Ln this stu
dy, axis II diagnoses were made on a heterogenous clinical sample of 3
70 patients entering treatment for substance use disorders. Axis II di
agnoses were made according to DSM-III-R criteria using the Structured
Clinical Interview for DSM-III-R (SCID-IT), which was modified to det
ermine, on an item-by-item basis, whether symptoms were attributed to
subjects' substance use disorders or independent of these disorders. T
he majority (57.0%) of substance use disorder patients met criteria fo
r at least one comorbid axis II disorder, with cluster B (45.7%) being
particularly prominent, especially antisocial personality disorder (A
SP) (27.0%) and borderline personality disorder (BPD) (18.4%). Notably
, inclusion of SR symptoms led to a substantial number of newly diagno
sed cases, especially for ASP (19.2%) and BPD (11.4%). Including SR sy
mptoms improved the reliability of ASP and did not change the reliabil
ity of BPD diagnoses. Generally, patients with SR and independent pers
onality disorders had a similar clinical profile.