The authors compared 9-, 16, 26-, and 52-week outcomes for two randoml
y assigned groups of nicotine-dependent subjects: 1) nicotine patch pl
us four smoking cessation sessions with a nurse-practitioner giving ad
vice and instruction (n = 36; moderate-intensity condition, MI); or 2)
the foregoing treatments plus 16 weekly individual cognitive/behavior
al relapse-prevention therapy sessions (n = 33; high-intensity conditi
on, HI). Patch completion rates were 69.7% in the HI group and 55.6% i
n the MI group (NS). Self-reported abstinence rates at the four follow
-up points were comparable for the two treatment groups; HI: 39%, 36%,
36%, and 36%; MI: 44%, 28%, 25%, and 28%, respectively. There was som
e indication that MI patients with high nicotine dependence had lower
abstinence rates than highly dependent HI patients.