BATH-PUVA THERAPY IN 3 PATIENTS WITH SCLEREDEMA ADULTORUM

Background: Scleredema adultorum (SA) is a rare connective tissue diso rder for which no treatment has proven to be effective. Objective: Our purpose was to determine the effect of bath-PUVA therapy on SA.Method s: Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline a nd after treatment. Results: All three patients showed substantial cli nical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm(2)). Ultrasonography showed signif icant reduction in both skin thickness and density. Conclusion: Bath-P UVA therapy appears to be effective in the treatment of SA.