Background and Objectives. Selective sympathetic denervation during ep
idural anesthesia results in a small, active gut. These changes can al
so result in selective activity in one segment of the gut that is abse
nt in other segments. Case Report. A 61-year-old male was scheduled fo
r bilateral total knee replacement during epidural anesthesia. Followi
ng onset of the epidural block, he experienced severe left-sided chest
pain. Surgery was canceled. A portable chest radiograph revealed a wi
dened mediastinum, and he underwent angiography to rule out a dissecti
ng thoracic aortic aneurysm. The left subclavian artery could not be v
isualized, and an MRI was obtained, which was normal. After his return
to the intensive care unit, he had a large bowel movement and his che
st pain resolved. Conclusion. Selective activity of the gastrointestin
al tract during the onset of epidural anesthesia created a visceral pa
in, which effectively simulated pain with a cardiovascular origin.