Fourier-transform infrared spectroscopy, using the diamond cell techni
que, has been shown to be a useful tool for the analysis of small samp
les. The diamond cell can be used both in an infrared microscope and i
n a microbeam compartment. In our laboratory both techniques have been
applied to forensic and industrial analysis and some examples are rep
orted. Sample preparation normally consists of physical separation wit
h the help of tungsten needles, microtoming techniques after embedding
the samples in paraffin blocks, or the use of solvents to extract som
e compounds before evaporation on different kinds of plate. The diamon
d cell technique seems to provide good results for all samples analyse
d.