Objectives. Although the clinical presentation and physical examinatio
n findings in patients with lymphoma or leukemia involving the prostat
e have been described previously, the transrectal ultrasound appearanc
e of hematolymphoid malignancies involving the prostate has not been p
reviously described. Methods. Nine patients with prostate cancer diagn
osed by transrectal ultrasound-guided prostate biopsies were found to
have hematolymphoid malignancies involving the prostate at the time of
subsequent radical prostatectomy and pelvic lymph node dissection. Th
e ultrasound images and prostate needle biopsy results are presented.
Results. Prospective analysis of transrectal ultrasound images reveale
d no abnormality other than hypoechogenicity typical of prostate cance
r in 7 of the 9 patients (77.8%). In 2 patients, the ultrasound images
were free of any abnormalities. In 2 of the 9 patients (22.2%), the p
rostate needle biopsies demonstrated suspicious lymphocytic infiltrate
in addition to prostate cancer. Conclusions. Transrectal ultrasound d
oes not detect hematolymphoid malignancies involving the prostate. Ult
rasound-guided biopsies of the prostate have a very low rate of detect
ing these malignancies. (C) 1998, Elsevier Science Inc. All rights res
erved.