Ma. Alfieri et al., SELENIUM AND ZINC LEVELS IN SURGICAL PATIENTS RECEIVING TOTAL PARENTERAL-NUTRITION, Biological trace element research, 61(1), 1998, pp. 33-39
The zinc and selenium levels of 40 surgical patients were monitored pr
e- and post-TPN. The initial selenium level was low normal, and the in
itial zinc level was also low. Both selenium and zinc are potent antio
xidants involved in cellular defense against free radicals. Surgical p
atients are at risk for selenium and zinc deficiencies secondary to bo
th increased needs and losses. TPN blood work protocols should include
monitoring of selenium and zinc with supplementation of the nutrient
solutions, as required.