1,3,4-THIADIAZOLE DERIVATIVES - PART 8 - BINUCLEAR COMPLEXES OF CU(II), MN(II), CO(II), NI(II) AND ZN(II) WITH A SCHIFF-BASE DERIVED FROM 5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE
M. Brezeanu et al., 1,3,4-THIADIAZOLE DERIVATIVES - PART 8 - BINUCLEAR COMPLEXES OF CU(II), MN(II), CO(II), NI(II) AND ZN(II) WITH A SCHIFF-BASE DERIVED FROM 5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Revue Roumaine de Chimie, 42(9), 1997, pp. 727-732
Binuclear complexes of the type CuML2 (M = Mn(II), Co(II), Ni(II) and
Zn(II); L = the dianion of the Schiff base obtained by condensation of
5-amino-1,3,4-thiadiazole-2-sulfonamide with 2-ketoglutaric acid) wer
e prepared and characterised by standard procedures. All these derivat
ives possess good inhibitory properties towards the zinc enzyme carbon
ic anhydrase.