C. Jenkinson et al., HOW SHOULD WE EVALUATE HEALTH-STATUS - A COMPARISON OF 3 METHODS IN PATIENTS PRESENTING WITH OBSTRUCTIVE SLEEP-APNEA, Quality of life research, 7(2), 1998, pp. 95-100
The purpose of this paper is to compare three approaches to the measur
ement of patient-reported health status which produce summary scales o
f health status: the Patient-generated Index (PGI) is a measure of ind
ividual quality of life (QoL), the EuroQol is a measure of QoL the res
ults of which are weighted by utility values gained from community sur
veys and the SF-36 which produces two summary scales of health status
(the physical component summary (PCS) and the mental component summary
(MCS) scores). A follow-up interview survey of patients with obstruct
ive sleep apnoea (OSA) was conducted. The patients received continuous
positive airways pressure therapy (CPAP) between the two administrati
ons of the questionnaires. One hundred patients presenting with OSA an
d who were suitable for CPAP therapy were asked if they would take par
t in the study. The results on the PGI, EuroQol EQ-5D utility weighted
scores and 'thermometer' scores and SF-36 physical and mental summary
scores were measured. Eighty-nine respondents provided sufficient dat
a to calculate PGI and EuroQol scores and 86 patients provided suffici
ent data to calculate SF-36 summary scores. The PGI indicated substant
ial improvement after CPAP treatment whereas the EuroQol indicated lit
tle or no improvement on either utility weighted or thermometer scores
. The SF-36 PCS and MCS scores were lower than those of the general po
pulation at baseline, but had improved to the normative levels after t
reatment. The EuroQol provided a substantially different picture of ch
ange to either of the ones gained from the SF-36 or PGI. It is suggest
ed that the EuroQol does not contain questions which relate to importa
nt aspects of health and well-being and may not accurately reflect the
health state of individuals. Consequently, caution must be exercised
to assure that an appropriate instrument has been employed when using
health outcomes data to assess or prioritize available health care tre
atments.