Pulmonary angiography (PA) for decades has been accepted as the gold s
tandard for the diagnosis of pulmonary embolism (PE). Apprehensions th
at the procedure is expensive, invasive and thus associated with both
fatal and non-fatal complications has more or less limited its use to
patients Presenting a non-diagnostic lung scan. However, this opinion
originates from earlier-studies. Increasing clinical demands for faste
r and safer diagnostics, together with improved techniques and safer c
ontrast media, has led to an increased use of PA. In order to evaluate
the complication rate, we retrospectively studied the case records of
707 consecutive patients who had undergone PA. During 1940-1994, 728
patients underwent PA at Danderyd End Huddinge University Hospital. Se
lective pulmonary angiography (cine or digital subtraction angiography
), non-ionic, low-osmolar contrast media and modern pigtail catheters'
were used. Standard volumes were 40 ml at 2 s for each injection. Pre
ssure measurements were made in 376 patients. A test injection was mad
e in all patients in order to assess the flow rate. Experienced radiol
ogists as well as residents performed the examinations and a total of
707 angiography protocols and clinical records were available for revi
ew in search of complications associated with the procedure. No deaths
occurred. One major non-fatal complication (bleeding in the groin req
uiring surgery) was reported in one case. Moderate/minor complications
(i.e. transient cardiac failure, minor haematomas, urticaria and occu
rred in 10 patients (1.4%). With modern contrast media and technique,
pulmonary angiography is a safe procedure.