NAKED-EYE DETECTABLE CHIRAL RECOGNITION USING A CHROMOGENIC RECEPTOR

This article is concerned with our recent achievement in developing sy nthetic chromogenic receptors for optical active amines and amino acid derivatives. Pre-organized (S)-1,1'-bi-2-naphthyl- and bis(indophenol )-derived calix[4]crown 1a shows naked-eye detectable chiral recogniti on between those enantiomers. The spectroscopic properties are reporte d, as well as an estimation of the enantioselectivity using an HPLC eq uipped with a chiral packing column.