CONTINUOUS MUSCLE-FIBER ACTIVITY - A CASE TREATED WITH ACETAZOLAMIDE

A case is reported of the continuous muscle fibre activity syndrome, w hich includes a group of disorders characterised by sustained motor un it activity due to hyperactivity of peripheral nerve motor axons. In t his patient the muscle stiffness and myokymic movements were successfu lly treated with acetazolamide, which acts as a membrane stabiliser ei ther by blockade of chloride and bicarbonate membrane transport or by producing kaliuresis and raising the transmembrane potential by decrea sing extracellular potassium.