DETERMINATION OF PARTICLE SEDIMENTATION-RATE BY ULTRASONIC INTERFEROMETRY - ROLE OF PARTICLE-SIZE, DENSITY AND VOLUME FRACTION

Citation
Sm. Razavian et al., DETERMINATION OF PARTICLE SEDIMENTATION-RATE BY ULTRASONIC INTERFEROMETRY - ROLE OF PARTICLE-SIZE, DENSITY AND VOLUME FRACTION, Biorheology, 34(4-5), 1997, pp. 349-362
Citations number
28
Categorie Soggetti
Biophysics,"Engineering, Biomedical",Hematology
Journal title
ISSN journal
0006355X
Volume
34
Issue
4-5
Year of publication
1997
Pages
349 - 362
Database
ISI
SICI code
0006-355X(1997)34:4-5<349:DOPSBU>2.0.ZU;2-X
Abstract
The sedimentation rate (SR) of non-aggregated spherical particles in s uspension was determined using an ultrasonic interferometry technique (Echo-Cell); this method is based on A-mode echography and measures th e rate of formation of a sediment on a solid plate during settling. Th e particle accumulation rate, which is related to SR, is obtained from the interference of two waves reflected by two interfaces: one betwee n the plate and the sediment and the other between the sediment and th e suspension. Studies were carried out at 25 degrees C using latex sph eres of different diameters (7 to 20 mu m) and densities (1.062 to 1.1 90 g/cm(3)) suspended in distilled water at various volume fractions ( 1% to 5%). As anticipated by the Stokes model, linear relations were f ound between SR and both particle density and the square of particle r adius. Experimental SR values decreased with increasing suspension par ticle concentration; these concentration effects were in good agreemen t with those predicted by the Steinour model. Our results thus serve t o validate the theoretical aspects of the Echo-Cell method and suggest its usefulness as a tool for studies of RBC interaction and RBC aggre gation. (C) 1997 Elsevier Science Ltd.