It has been well documented that the prevalence of certain electrocard
iographic (EGG) findings among individuals free of coronary heart dise
ase (CHD) differs by race. However, it is not known whether these diff
erences exist independently of CHD risk factors (e.g., hyper;tension).
We examined the ECG tracings of 2,686 apparently healthy, middle-aged
African-American and white men and women who participated in the Athe
rosclerosis Risk in Communities Study and were at low risk of CHD. Usi
ng the Minnesota Code, among men, 46% of African-Americans, but only 2
5% of whites, had a minor ECG finding (p <0.001). In women, 32% of Afr
ican-Americans and 23% of whites had a minor ECG finding (p <0.01). Sp
ecifically, the age-adjusted prevalences of high-amplitude R wave, ST
elevation, T-wave findings, and prolonged P-R interval were statistica
lly significantly higher in African-Americans. As for continuous ECG m
easurements, the R wave in leads V-5 and V-6, the S wave in V-1, the J
-point amplitude in leads V-2 and V-5, the P-R interval, and the Corne
ll voltage (\S V-3\ + R aVL) for left ventricular hypertrophy were all
significantly greater in African-Americans than in whites. However, i
n both men and women, the heart rate corrected QT interval was shorter
in African-Americans than in whites. All of these findings remained s
tatistically significant after further adjustment for traditional CHD
risk factors. These results suggest that racial differences in electro
cardiograms may not be explained entirely by differences in establishe
d CHD risk factors, and because current diagnostic ECG criteria are la
rgely based on data from middle-aged white men and women, race should
be considered in the interpretation of ECG findings. (C) 1998 by Excer
pta Medica, Inc.