DISTINCT LIGHT-MICROSCOPIC CHANGES IN HUMAN IMMUNODEFICIENCY VIRUS-ASSOCIATED NEMALINE MYOPATHY

Authors
FEINBERG DM SPIRO AJ WEIDENHEIM KM
Citation
Dm. Feinberg et al., DISTINCT LIGHT-MICROSCOPIC CHANGES IN HUMAN IMMUNODEFICIENCY VIRUS-ASSOCIATED NEMALINE MYOPATHY, Neurology, 50(2), 1998, pp. 529-531
Citations number
10
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
50
Issue
2
Year of publication
1998
Pages
529 - 531
Database
ISI
SICI code
0028-3878(1998)50:2<529:DLCIHI>2.0.ZU;2-F
Abstract
The purpose of this study was to compare histologic characteristics of congenital nemaline myopathy (CNM), adult-onset nemaline myopathy (AO NM), and human immunodeficiency virus-associated adult-onset nemaline myopathy (HAONM). There was no difference between the pathology of CNM and AONM; however, HAONM had distinctive pathologic features by light microscopy. The fibers in HAONM showed marked intrasarcoplasmic chang es, including small vacuoles and granular degeneration.