EFFECTS OF AMPHETAMINE ON THE DEVELOPMENT OF MOLONEY SARCOMA VIRUS-INDUCED TUMORS IN MICE

Authors
FREIREGARABAL M NUNEZIGLESIAS MJ REYMENDEZ M PEREIRORAPOSO MD RIVEIRO P FERNANDEZRIAL JC LOSADA C GANDOY M MAYAN JM
Citation
M. Freiregarabal et al., EFFECTS OF AMPHETAMINE ON THE DEVELOPMENT OF MOLONEY SARCOMA VIRUS-INDUCED TUMORS IN MICE, Oncology Reports, 5(2), 1998, pp. 381-383
Citations number
24
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
5
Issue
2
Year of publication
1998
Pages
381 - 383
Database
ISI
SICI code
1021-335X(1998)5:2<381:EOAOTD>2.0.ZU;2-U
Abstract
Experiments were conducted to evaluate the effects of amphetamine (0.4 mg/kg) on the development of autochthonous tumors induced by the Molo ney sarcoma virus (MSV) in Balb/c female mice. Enhancement of MSV-indu ced tumor incidence and tumor growth was observed, together with a del ay in the usual prompt regression of the tumors, when mice were daily injected with amphetamine for 3 days after MSV-inoculation. However, n o effects of amphetamine on tumor development were observed when it wa s administered during the 3 days before tumor inoculation.