SYNTHESIS AND EVALUATION OF 1,5-BENZODIAZEPINES WITH BRIDGED CYCLOALKYL SUBSTITUENTS AT THE N-1 POSITION AS POTENT AND SELECTIVE CCK-B LIGANDS

Authors
FINIZIA G DONATI D PENTASSUGLIA G POLINELLI S TARZIA G TRANQUILLINI ME URSINI A
Citation
G. Finizia et al., SYNTHESIS AND EVALUATION OF 1,5-BENZODIAZEPINES WITH BRIDGED CYCLOALKYL SUBSTITUENTS AT THE N-1 POSITION AS POTENT AND SELECTIVE CCK-B LIGANDS, Archiv der pharmazie, 331(1), 1998, pp. 41-44
Citations number
23
Categorie Soggetti
Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
331
Issue
1
Year of publication
1998
Pages
41 - 44
Database
ISI
SICI code
0365-6233(1998)331:1<41:SAEO1W>2.0.ZU;2-#
Abstract
The synthesis and biological evaluation of 3-ureido and 3-carbamate de rivatives of 1,5-benzodiazepines bearing bridged cycloalkyl substituen ts at N-1 are reported. Their activity as CCK-B receptor ligands is br iefly discussed.