To review the impact of case management programs on health care resour
ce use; their impact on patient satisfaction, quality of life, and fun
ctional status (patient-centered outcomes); and their cost-effectivene
ss, we reviewed the English language literature utilizing the followin
g MEDLINE and Health-STAR headings: case management, patient care plan
ning, patient-centered care, disease management, care management, and
managed care programs. Bibliographies of relevant articles were also r
eviewed, Only randomized controlled trials were included. Data were ex
tracted manually from relevant publications and are presented descript
ively because formal, quantitative methods were not applicable. Nine s
tudies met our inclusion criteria, Of the seven studies examining case
management's impact on health resource use, only two found a positive
effect, Both successful programs targeted patients with specified dis
ease conditions and care was supervised by a medical subspecialist. No
ne of the programs targeting general disease conditions or supervised
by generalists reported a positive effect. All six studies examining p
atient-centered outcomes reported a positive impact. These effects wer
e unrelated to the patient's conditions or the study personnel. Both s
tudies examining clinical parameters found a positive impact, Only thr
ee studies examined costs: all reported nonsignificant cost savings, W
hile case management programs offer theoretical benefits, few examples
of successful programs were found. Positive effect was related to dis
ease condition and specialty training of study personnel. Patient-cent
ered outcomes were often improved upon but at unknown cost, Further mu
ltisite clinical trials are needed to define case management's role in
our future health care system.