Objective: To describe an accurate and reproducible method to quantify
a patient's subjective experience of breast pain. Design: Prospective
diary study. Setting: Military tertiary care hospital. Patients: Thir
ty female military health care beneficiaries from the Waiter Reed Army
Medical Center, Washington, DC, gynecology and general surgery clinic
s.Main Outcome Measures: Daily mastalgia was recorded using a visual a
nalog scale and menstrual symptoms were measured using a daily questio
nnaire. These measures were correlated with results of a screening que
stionnaire completed prior to study entry. Results: Patients identifie
d as having cyclical mastalgia based on the screening questionnaire (n
= 15) were found to have higher peak perimenstrual mastalgia accordin
g to their daily diaries than patients who did not meet diagnostic cri
teria (n = 15) (5.3 +/- 0.7 vs 3.5 +/- 0.5, P < .001). Applying the sa
me criteria used in the screening questionnaire to the diary data, 17
of 30 patients met diagnostic criteria for cyclical mastalgia. The abi
lity of the screening questionnaire to predict the results of the pros
pective diary data was calculated, and positive and negative predictiv
e values were 73 % and 60 %, respectively. Most patients with cyclical
mastalgia also have other perimenstrual psychological and somatic com
plaints, although a subset of patients has high levels of mastalgia wi
th minimal associated symptoms. Conclusions: Accurate assessment of ma
stalgia cannot be done with a retrospective questionnaire and requires
prospective diary evaluation, owing to the variable and subjective na
ture of symptoms and recall bias. A daily visual analog scale provides
reproducible results and is easy for patients to use.