Neurological Examination Abnormalities (NEA) are prevalent in schizoph
renia, but the significance of this is obscured by methodological prob
lems. The Neurological Evaluation Scale (NES), the most widely used st
ructured neurological examination in schizophrenia research, has had l
imited study of its inter-rater reliability (IRR). An augmented versio
n of the NES was jointly administered (one examiner-rater and one obse
rver-rater) by three pairs of psychiatrists to two populations of pati
ents with idiopathic psychotic disorders. In addition to the ordinal a
nd categorical data yielded by the original NES, continuous data were
recorded in one of the series. Reliability analyses of our populations
and a previously published study, reveal consistently adequate IRR in
12 of the 26 items assessed, and inconsistently adequate IRR in an ad
ditional 11. Consistent with studies using other NEA schedules, IRR wa
s unacceptably low for some items that rely on subjective severity rat
ings. Certain rare abnormalities, which posed difficulties for the est
imation of IRR, are probably not generally useful in the study of schi
zophrenia. Reliability estimates of continuous, ordinal and dichotomou
s data were comparable in most cases. We recommend that certain items
from the NES be deleted, and that other studies of NEA in psychiatry f
ollow similar procedures before undertaking further analyses. (C) 1998
Elsevier Science B.V.