The presence of caprine arthritis and encephalitis (CAE) in Spain has
never been officially acknowledged hut it is suspected, Goats have bee
n imported from other European countries with a high prevalence of the
disease, mainly France, and they might have introduced the disease in
to the indigenous goat population. A serological survey of caprine art
hritis and encephalitis virus antibodies was carried out in 22 volunte
er dairy Murciano-Granadina goat herds; 2513 lactating goats were test
ed with an agar gel immunodiffusion test, and 12.1 per cent were found
to be positive, Five of the herds were free of infection, six had a l
ow prevalence of the disease, Five had a medium prevalence and six had
a high prevalence, Five seropositive goats with clinical signs of CAE
were studied, Macroscopic and microscopic lesions similar to those de
scribed fur CAE were detected in all five goats and a cytopathic effec
t typical of CAE virus was observed in primary explant cultures from f
our of them.