S. Gordon et al., SYNTHESIS AND IN-VITRO ANTHELMINTIC ACTIVITY AGAINST NIPPOSTRONGYLUS-BRASILIENSIS OF NEW 2-AMINO-4-HYDROXY-DELTA-VALEROLACTAM DERIVATIVES, Il Farmaco, 52(10), 1997, pp. 603-608
The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam deri
vatives is described (compounds 4 to 10). These compounds showed a hig
h anthelmintic in vitro activity against the Nippostrongylus brasilien
sis model.