SYNTHESIS AND IN-VITRO ANTHELMINTIC ACTIVITY AGAINST NIPPOSTRONGYLUS-BRASILIENSIS OF NEW 2-AMINO-4-HYDROXY-DELTA-VALEROLACTAM DERIVATIVES

Citation
S. Gordon et al., SYNTHESIS AND IN-VITRO ANTHELMINTIC ACTIVITY AGAINST NIPPOSTRONGYLUS-BRASILIENSIS OF NEW 2-AMINO-4-HYDROXY-DELTA-VALEROLACTAM DERIVATIVES, Il Farmaco, 52(10), 1997, pp. 603-608
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
0014827X
Volume
52
Issue
10
Year of publication
1997
Pages
603 - 608
Database
ISI
SICI code
0014-827X(1997)52:10<603:SAIAAA>2.0.ZU;2-J
Abstract
The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam deri vatives is described (compounds 4 to 10). These compounds showed a hig h anthelmintic in vitro activity against the Nippostrongylus brasilien sis model.