SYNTHESIS AND TRANSFORMATIONS OF METHYL (E)-2-(ACETYLAMINO)-3-CYANOPROP-2-ENOATE UND METHYL (E)-2-(BENZOYLAMINO)-3-CYANOPROP-2-ENOATE, VERSATILE REAGENTS FOR THE PREPARATION OF POLYFUNCTIONAL HETEROCYCLIC-SYSTEMS

Authors
PIZZIOLI L ORNIK B SVETE J STANOVNIK B
Citation
L. Pizzioli et al., SYNTHESIS AND TRANSFORMATIONS OF METHYL (E)-2-(ACETYLAMINO)-3-CYANOPROP-2-ENOATE UND METHYL (E)-2-(BENZOYLAMINO)-3-CYANOPROP-2-ENOATE, VERSATILE REAGENTS FOR THE PREPARATION OF POLYFUNCTIONAL HETEROCYCLIC-SYSTEMS, Helvetica Chimica Acta, 81(2), 1998, pp. 231-235
Citations number
24
Categorie Soggetti
Chemistry
Journal title
Helvetica Chimica Acta → ACNP
ISSN journal
0018019X
Volume
81
Issue
2
Year of publication
1998
Pages
231 - 235
Database
ISI
SICI code
0018-019X(1998)81:2<231:SATOM(>2.0.ZU;2-Y
Abstract
Methyl (E)-2-(acetylamino)-3-cyanoprop-2-enoate (2a) and its 2-benzoyl analog 2b were prepared from the corresponding methyl (Z)-2-(acylamin o)-3-(dimethylamino)propenoates 1. Multifunctional compounds Z are ver satile synthons for preparation of polysubstituted heterocyclic system s such as pyrroles 4, pyrimidines 5 and 6, pyridazines 7, pyrazoles 8, 9, and 11, and isoxazoles 10.