The key advances in DNA diagnostics during the past year are technique
s which will lead to advanced throughput without sacrificing sensitivi
ty: miniaturization of samples to reduce material cost and preparation
time, and parallelization through use of measurement arrays. The most
promising gains have come in the areas of DNA arrays and mass spectro
metry, where differential sequencing measurements are now possible. (C
) Current Biology Ltd ISSN 0958-1669.