HEMIAMINAL GENERATED BY HYDRATION OF KETONE-BASED NITRONE AS AN N,O-CENTERED NUCLEOPHILE IN ORGANIC-SYNTHESIS

Authors
ISHIKAWA T NAGAI K SENZAKI M TATSUKAWA A SAITO S
Citation
T. Ishikawa et al., HEMIAMINAL GENERATED BY HYDRATION OF KETONE-BASED NITRONE AS AN N,O-CENTERED NUCLEOPHILE IN ORGANIC-SYNTHESIS, Tetrahedron, 54(11), 1998, pp. 2433-2448
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
11
Year of publication
1998
Pages
2433 - 2448
Database
ISI
SICI code
0040-4020(1998)54:11<2433:HGBHOK>2.0.ZU;2-K
Abstract
Isoxazolidines that are useful precursors for beta-amino acids have be en prepared relying on intermolecular amino Michael addition-intramole cular S(N)2 displacement employing hydroxylamine or hydrate of ketone- based nitrone as an N- and O-centered binucleophile. (C) 1998 Elsevier Science Ltd. All rights reserved.