Alpha hydroxy acids (AHAs) have been used as cosmetic agents since anc
ient times. In low concentrations AHAs cause a decrease in corngocyte
cohesion. In higher concentrations they result in epidermolysis and up
per dermal changes, producing a vibrant, less wrinkled, and more unifo
rmly colored skin. The method of application is important as is decrea
sing pH to increase the AHA bioavailability.