ABNORMALITIES OF BIOGENIC-AMINES AFFECTING THE METABOLISM OF SEROTONIN AND CATECHOLAMINES

Authors
LAMERS KJB WEVERS RA
Citation
Kjb. Lamers et Ra. Wevers, ABNORMALITIES OF BIOGENIC-AMINES AFFECTING THE METABOLISM OF SEROTONIN AND CATECHOLAMINES, Multiple sclerosis, 4(1), 1998, pp. 37-38
Citations number
5
Categorie Soggetti
Clinical Neurology
Journal title
Multiple sclerosis → ACNP
ISSN journal
13524585
Volume
4
Issue
1
Year of publication
1998
Pages
37 - 38
Database
ISI
SICI code
1352-4585(1998)4:1<37:AOBATM>2.0.ZU;2-H
Abstract
This paper describes the relevance of measuring biogenic amine metabol ites in cerebrospinal fluid in order to detect inborn errors affecting catecholamines and serotonin biosynthesis. Defects in tetrahydrobiopt erin and a deficiency of aromatic L-amino acid decarboxylase, tyrosine hydroxylase or dopamine-beta-hydroxylase ore candidate inborn errors for neurotransmitter metabolites screening. This investigation has to be considered in any child with motor retardation and extrapyramidal s igns.