E. Frank et al., POSTOPERATIVE EPIDURAL ANALGESIA FOLLOWING RADICAL RETROPUBIC PROSTATECTOMY - OUTCOME ASSESSMENT, Journal of surgical oncology, 67(2), 1998, pp. 117-120
Background and Objectives: We retrospectively examined the effects of
epidural analgesia on patients undergoing radical retropubic prostatec
tomy (RRP). Methods: Patients (203) underwent radical retropubic prost
atectomy under either general or epidural anesthesia alone or a combin
ed general epidural technique. Of those, 143 had an epidural catheter
placed and underwent radical retropubic prostatectomy under general an
esthesia followed by postoperative epidural analgesia (Group E+G). Twe
nty-eight patients had the operation under epidural anesthesia followe
d by epidural analgesia in the postoperative period (Group E). Thirty-
two patients had general anesthesia for the operation and postoperativ
e systemic analgesia (Group G). Results: There were no significant dif
ferences between the groups with respect to age, height, weight, ASA s
tatus, or operation time. The length of postoperative hospital stay wa
s significantly longer in the general anesthesia group patients as com
pared to the other two groups (P < 0.05). Intraoperative blood loss an
d blood replacement were significantly higher in the general anesthesi
a group (P < 0.001). There were no significant differences between the
groups with respect to return of bowel function postoperatively, or i
ncidence of complications. Conclusions: Epidural anesthesia and analge
sia following radical retropubic prostatectomy have demonstrated a num
ber of beneficial effects. These include decreased blood loss and shor
ter hospital stay. (C) 1998 Wiley-Liss, Inc.