Contiguous orthonormal arterial cross sections, segment lengths, and c
urvature were semiautomatically quantified from helical computed tomog
raphic (CT) angiographic data in phantoms and two patients. Measuremen
ts of mean diameter and curvature correlated with reference values (r(
2) = .99), and mean fractional errors were 0.07 and 0.06 for mean diam
eter and curvature measurements, respectively. Volumetric measurement
showed a potential to increase the accuracy, precision, and diagnostic
utility of CT angiography.