Objective To determine whether there is vesico-ureteric reflux during
voiding in patients who had undergone an ileal bladder substitution af
ter cystectomy. Patients and methods The study comprised 15 patients (
13 men and two women) who had undergone radical cystectomy and constru
ction of a Studer ileal neobladder. At 1-24 months (median 4) after th
e operation indirect radionuclide cystography (IRC) was performed afte
r isotopic renography (using 99m-technetium mercapto-acetyltriglycine)
and voiding cystourethrography (VCUG), Results None of the patients h
ad reflux during voiding, either on IRC or on VCUG. Renal function and
morphology remained stable in all patients, Despite bacteriuria occur
ring in four patients, no episode of pyelonephritis was reported. Conc
lusion There was no vesico-ureteric reflux during voiding in patients
with a Studer ileal bladder substitution. However, long-term follow-up
is needed to finally determine whether an antirefluxive ureteric impl
antation is required to protect the upper urinary tract in patients wi
th ileal low-pressure bladder substitutions.